Cheap Price Manufacturer Supply Toremifene Citrate 89778-27-8
Synonyms: FC 1157a; Fareston; NK 622; NSC 613680
CAS: 89778-27-8
Molecular Formula: C26H28ClNO·C6H8O7
Molecular Weight: 598.09
Melting Point: 158-164 ºC
Boiling Point: 535.1 ºC at 760 mmHg
Density: 1.045g/cm3
Refractive index: 1,416-1,418
Appearance: White or almost white powder
Toremifene Citrate(Fareston) is a member of a category, family, and class of drugs that are known as SERMs (Selective Estrogen Receptor Modulators). SERMs fall under an even broader category of drugs that are known as anti-estrogens, and the cousin family of SERMs (that also fall under anti-estrogens) are aromatase inhibitors, commonly abbreviated as AIs. SERMs include compounds such as Nolvadex and Clomid (Clomiphene Citrate). Aromatase inhibitors (AIs) include compounds such as Arimidex ) Aromasin, (Femara). Although the two fall under the category of anti-estrogens, they are both sub-categories that branch off into their own families, as SERMs and AIs differ greatly in their mechanism of action within the human body concerning how they control or block Estrogen. There has been much misunderstanding and misconception in previous decades as to what each of these do, and this should always be first clarified to the reader before describing Toremifene.
Toremifene citrate is an oral selective estrogen receptor modulator (SERM) which helps oppose the actions of estrogen in the body. Licensed in the United States under the brand name Fareston, toremifene citrate is FDA-approved for use in advanced (metastatic) breast cancer. It is also being evaluated for prevention of prostate cancer under the brand name Acapodene.
It has already been covered that Toremifene is a SERM, and serves to block Estrogen at various receptor sites in certain tissues within the body (breast tissue in particular). As a layman explanation, Toremifene pretends to be a 'fake' Estrogen that occupies Estrogen receptors within breast tissue. With these receptors occupied by Toremifene, real Estrogen cannot perform their jobs there.
Toremifene does not reduce total blood plasma levels of Estrogen. In addition to being antagonistic to Estrogen receptors in breast tissue, it is also antagonistic to Estrogen at the hypothalamus gland (this essentially 'tricks' the hypothalamus into thinking there is little or no circulating Estrogen levels in the body, causing it to increase its manufacture of Testosterone so that it can utilize aromatization to restore these levels.
Toremifene is also agonistic to Estrogen receptors in other tissues in the body (within the liver in particular). This means that whileToremifene will act as an anti-estrogen in breast tissue and the hypothalamus, it will act as an Estrogen within the liver. This can have beneficial impacts especially during an anabolic steroid cycle, such as improving and shifting cholesterol levels into a more favorable range.
Hjtc (Xiamen) Industry Co., Ltd.
Xiamen Huayongjian Biotechnology Co., Ltd.
Contacts: June & Eason
Whatsapp:+8618206063252; +8618759200098
E-mail: eastern002@126.com;
eason_hjtc@126.com
Web site:https://www.steroidpowder-hjtc.com/
http://www.safeststeroid.com/
http://www.glassviallabels.com/
https://hjtc-printing.en.made-in-china.com/
Test items | Quality requirements | Results |
Description | White or like white crystalline powder | White crystalline powder |
Solubility | Freely soluble in pyridine and acetic acid(100), sparingly soluble in methanol, slightly soluble in ethanol, very slightly soluble in water, and practically insoluble in diethyl ether | Freely soluble in pyridine and acetic acid(100), sparingly soluble in methanol, slightly soluble in ethanol, very slightly soluble in water, and practically insoluble in diethyl ether |
Melting point | 159~163ºC | 159.0~160.5ºC |
Identification | ||
(a)Positive reaction | Must comply | Complies |
(b)Positive reaction | Must comply | Complies |
(c) UV | There is the strongest absorption at the wavelength of 234~238nm and 275~278nm. | There is the strongest absorption at the wavelength of 236.8nm and 276.2nm. |
(d) IR | There is absorption at 1741, 1703, 1585, 1241 and 706cm-1 . | There is absorption at 1741, 1703, 1585, 1241 and 706cm-1 . |
Purity | 99% | |
(a) Relative substances | ||
E-isomer | ≤0.5% | 0.001% |
Total relative substances | ≤1.0% | 01% |
(b)Heavy metals | ≤10ppm | <10ppm |
Loss on drying | ≤1.0% | 0.1% |
≤0.089% | 0.0002% | |
Ethanol | ≤0.5% | 0 |
Acetone | ≤0.5% | 0.21% |
≤0.072% | 0.0001% | |
Chlorobenzen | ≤0.036% | 0 |
Benzene | ≤0.0002% | 0 |
Residue on ignition | ≤0.1% | 0.04% |
Assay | ≥98.5% (Calculated by C26H28ClNO .C6H8O7) | 99.7% |
Conclusion: The results comply with the requirements of the export standard. |
1) Orders: For mutiple items and large volume clients, substantial discounts can be arranged on an individual basis.
2) Shipping method: Super discreet packaging, to ensure safe delivery.
3) Export: Our products have exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Australia, Japan, Korea and many other countries, over 5000kg each month.
4) Stock: Most of powders are in stock, Chargeable samples are available, could be shipped out within 24hours.
5) Shipment: High quality, good price, fast and safety delivery. Shipment by DHL, TNT, FEDEX, HKEMS, EMS, UPS,Aramex etc.
Make an order |
Please make clear what product and what quantity you need |
Mini Order |
Only 5g, 10 grams |
Quote |
Prices and Specification details(COA) would be offered for you to consider and confirm |
Payment ways |
Bitcoin, paypal, bank transfer, Wise Transfer, etc |
Delivery ways |
All Express Modes(EMS, DHL, TNT, FedEx, UPS, etc.) |
Shipping address |
Provide your Valid and Correct destination address info(if possible with post code, phone number). |
Packing |
Select best ways according to quantity and safety degree(Super discreet, professional and experienced) |
Lead time |
Within 12 hours upon receipt of payment |
Package pictures |
Photos of parcel would be offered to tell apart the items |
Tracking number |
Offered once it is released |
Shipping time |
3-7 working days (Door-to-Door) |
After-sale service |
24/7 Online for any problems |
1. Fastest delivery. We will deliver the products in 12 hours when we receive the payment.
2. Good delivery company. We use the legal delivery company so you can receive the product for sure.
3. Good package. Unique ways to ship 10grams to 100kg powders at one time to your destination. Fast and discreet shipment will be arranged for customs to pass Customs.
4. Professional team. Packing pictures and tacking code will be sent to you within 12 hours after receiving the payment. Updated tracking information will be provided every other day.
Adequate stock as we are the manufacturer
Strict quality control before products are allowed to sell
Worldwide shipping and delivery is guaranteed
Bitcoin ,Western Union,MoneyGram,Bank Transfer Accepted
EMS,UPS,DHL,Fedex,TNT,by air,by sea etc
All personal information is kept confidential
Photos of parcel and tracking number be offered timely
24/7 online service
You can ask us any question you doubt and we will reply within 12 hours.
Old tracking numbers of your country can be offered for your reference.
Variety of discreet packages can be offered for your choice,also we can give advice of which package and express is the safest to your country according to our years of experience.
All our deliveries are packaged plain without any descriptions or company names. None else know what is inside.
Products Name |
CAS |
Testosterone Series |
|
Testosterone |
58-22-0 |
Testosterone Acetate |
1045-69-8 |
Testosterone Cypionate |
58-20-8 |
Testosterone Decanoate |
5721-91-5 |
Testosterone Enanthate |
315-37-7 |
Testosterone Isocaproate |
15262-86-9 |
Testosterone Phenylpropionate |
1255-49-8 |
Testosterone Propionate |
57-85-2 |
Testosterone undecanoate |
5949-44-0 |
Sustanon 100 |
/ |
Sustanon 250 |
/ |
17α-Methyl-1-testosterone |
1965-4-3 |
1-Testosterone |
1965-6-5 |
Methyltestosterone (17A-hydroxyprogesterone) |
68-96-2 |
Fluoxymesterone |
76-43-7 |
Mesterolone |
521-11-9 |
4-Chlorotestosterone acetate |
855-19-6 |
Methyltestosterone |
58-18-4 |
Boldenone Series |
|
Boldenone |
846-48-0 |
Boldenone acetate |
/ |
Boldenone Cypionate |
/ |
Boldenone Propionate |
/ |
Boldenone undecylenate |
13103-34-9 |
Nandrolone Series |
|
Nandrolone |
434-22-0 |
Nandrolone 17-propionate |
7207-92-3 |
Nandrolone Cypionate |
601-63-8 |
Nandrolone Decanoate |
360-70-3 |
Nandrolone phenylpropionate |
62-90-8 |
Nandrolone undecylate |
/ |
Mestanolone |
521-11-9 |
Stanolone |
521-18-6 |
Trenbolone Series |
|
Tibolone |
5630-53-5 |
Trenbolone |
/ |
Trenbolone Acetate |
10161-34-9 |
Trenbolone Enanthate |
10161-33-8 |
Trenbolone Hexahydrobenzyl Carbonate |
23454-33-3 |
Methyltrienolone |
965-93-5 |
Drostanolone Series |
|
Drostanolone Enanthate |
521-12-0 |
Drostanolone Propionate |
521-12-0 |
Methasterone |
3381-88-2 |
Methenolone Series |
|
Methenolone Acetate |
434-05-9 |
Methenolone Enanthate |
303-42-4 |
Oral Series |
|
Anastrozole |
120511-73-1 |
Clomifene citrate (Clomid) |
50-41-9 |
Dianabol |
72-63-9 |
Exemestane |
107868-30-4 |
Letrozole |
112809-51-5 |
Oxandrolone |
53-39-4 |
Oxymetholone |
434-07-1 |
Turinabol-oral(4-Chlorodehydromethyltestosterone) |
2446-23-3 |
Stanozolol |
10418-03-8 |
Q1: Have your Product Quality been Approved by Third Party Lab?
A: Yes, All of our products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France etc. So you will be assured with Good Quality if you choose us.
Q2: How do you treat quality complaint?
A: First of all, our QC department will do strict examination of our export products by HPLC, UV, GC , TLC and so on in order to reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
Q3: How to cooperate with us?
You can contact us for cooperation through the website contact information, or contact with the salesmen in our company. We will connect you about the specific detail via email.
Q4: Do you Accept Sample Order?
A: Yes, we accept small order from 1g, 100g and 1kg for your evaluation quality of our goods.
Q5: Is there any discount?
A: Yes, as for old customers and larger quantity, we always support with great discounts and surprise.
Q6: Do you accept VISA business credit card ?
A: Sorry we don't accept VISA credit card,
we'd like to accept T/T , Moneygram , Western Union.
Q7: How long does it take to the goods arrived ?
A:It is Depending on your location,
For small order, please expect 5-7 days by DHL,UPS,TNT, FEDEX, EMS.
For mass order, please allow 5-8 days by Air, 20-35 days by Sea.
Q8: Do you have any reshipment policy ?
we have good after-sale service and re-shipment policy if the parcel lose.
Our long association with our clients has brought great benefits
We always take the upmost care in the packaging of our products
our clients will confirm this as even they struggle to find them without help at times.
But in spite of our best efforts it is still possible will seize a small number of packages.
In this circumstance we promise reship free to establish long term relationship
Q9: How to proceed order?
Let me konw the items, quantity and the destination contruy wihch help me to give you a right price
Please let me know the items you are looking for, quantity and the destination country. After you confirm all details of order, pay money 100% in advance and give us Shipping address. We arrange the shipment at first time after receive payment and offer you the tracking number for your goods, and we will supply after-sales service after you receive parcel.